SCHEMBL9066693

SCHEMBL9066693

O=C(O)C(CC(CO)C(O)O)=C(CC(CO)C(O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.38
PDE4A P27815 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.33
LMNA P02545 1/20 0.33
GRIK1 P39086 2/20 0.32
TET2 Q6N021 3/20 0.31
TET3 O43151 1/20 0.31
TET1 Q8NFU7 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GRIA4 P48058 1/20 0.30
GRIK3 Q13003 1/20 0.30
GRIK5 Q16478 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8043434 0.78 TET2 (0.52) OR51E2PDE4ALMNAGRIK1TET2
SCHEMBL9067150 0.76 LMNA (0.42) OR51E2PDE4ASLC22A6LMNAGRIK1
SCHEMBL9067380 0.76 LMNA (0.42) OR51E2PDE4ASLC22A6LMNAGRIK1
SCHEMBL9067155 0.76 LMNA (0.42) OR51E2PDE4ASLC22A6LMNAGRIK1
SCHEMBL8049140 0.72 OR51E2 (0.35) OR51E2SLC22A6GRIK1GRIA4GRIK3
SCHEMBL8045177 0.72 OR51E2 (0.35) OR51E2SLC22A6GRIK1GRIA4GRIK3
SCHEMBL8046521 0.72 OR51E2 (0.35) OR51E2SLC22A6GRIK1GRIA4GRIK3
SCHEMBL729097 0.69
SCHEMBL8051853 0.67 TP53 (0.40) SLC22A6GRIK1TET2SMN1; SMN2GRIA4
SCHEMBL5597687 0.67 TP53 (0.40) SLC22A6GRIK1TET2SMN1; SMN2GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0612773-B1 Thermoplastic resin composition and process for preparing modified polyolefin type resin MITSUBISHI CHEM CORP (JP) 1996-12-27 EP disclosed
US-5424359-A Aromatic vinyl polymer having alpha, beta-unsaturated carboxylate having a hydroxyl group grafted onto it, and saturated polyester MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1995-06-13 US disclosed
EP-0612773-A1 Thermoplastic resin composition and process for preparing modified polyolefin type resin MITSUBISHI CHEMICAL CORPORATION (JP) 1994-08-31 EP disclosed