Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991074 | 0.83 | BCHE (0.43) | SMN1; SMN2ALDH1A1GSK3BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1514013 | 0.70 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1GSK3BKDM4ECCNA2 | |
| SCHEMBL12680401 | 0.62 | BCHE (0.43) | SMN1; SMN2GSK3BLMNAMAPTRAB9A | |
| SCHEMBL13526011 | 0.62 | ALOX15 (0.46) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL19982874 | 0.61 | MAPK1 (0.44) | SMN1; SMN2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL422850 | 0.61 | ALOX15 (0.41) | SMN1; SMN2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL13525921 | 0.61 | ALOX15 (0.41) | SMN1; SMN2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL28848845 | 0.61 | ALOX15 (0.41) | SMN1; SMN2LMNAKDM4EMAPTRAB9A | |
| SCHEMBL27749673 | 0.61 | CTSK (0.54) | TSHR | |
| SCHEMBL13525916 | 0.60 | ALOX15 (0.39) | SMN1; SMN2ALDH1A1LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074259-A1 | TRIAZOLOTRIAZINES AND TRIAZOLOPYRAZINES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-18 | — | — | WO | disclosed |