Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | STK17B | O94768 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049599 | 0.86 | CYP1A2 (0.57) | TRPV1TDP1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL8043531 | 0.85 | METAP1 (0.49) | HIF1AGRM5SMN1; SMN2KDM4ELMNA | |
| SCHEMBL8041606 | 0.85 | HIF1A (0.51) | HIF1AGRM5SMN1; SMN2KDM4ELMNA | |
| SCHEMBL8045505 | 0.85 | HIF1A (0.45) | TRPV1F2F12HIF1AGRM5 | |
| SCHEMBL8032107 | 0.85 | HIF1A (0.45) | TRPV1HIF1AGRM5SMN1; SMN2KDM4E | |
| SCHEMBL8045497 | 0.82 | TRPV1 (0.44) | TRPV1F2F12HIF1AGRM5 | |
| SCHEMBL8043609 | 0.82 | HIF1A (0.47) | TRPV1F2F12HIF1AGRM5 | |
| SCHEMBL8042355 | 0.82 | HIF1A (0.47) | HIF1AGRM5SMN1; SMN2KDM4ELMNA | |
| SCHEMBL8043602 | 0.81 | GRM5 (0.54) | TRPV1HIF1AGRM5SMN1; SMN2KDM4E | |
| SCHEMBL8043550 | 0.81 | CYP1A2 (0.49) | TRPV1F2F12HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159974-A | LDL receptor gene expression promoters | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-12-12 | — | — | US | claimed |
| US-6159974-A | LDL receptor gene expression promoters | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-12-12 | — | — | US | disclosed |