SCHEMBL8043644

SCHEMBL8043644

COc1c(O)c(-c2cc(C)c(O)c(C)c2)cc(C)c1-c1cc(C)c(O)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 4/20 0.46
EPHX2 P34913 3/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
FYN P06241 2/20 0.43
PDE4A P27815 3/20 0.38
PDE4C Q08493 3/20 0.38
PDE4D Q08499 3/20 0.38
MGAM O43451 5/20 0.35
GAA P10253 5/20 0.35
SI P14410 5/20 0.35
MGAM2 Q2M2H8 5/20 0.35
ALOX5 P09917 2/20 0.34
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
AKR1B1 P15121 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8898211 0.79 MGAM (0.58) PDE4BPDE4APDE4CPDE4DMGAM
SCHEMBL5520610 0.79 CA1 (0.54) CA1CA2FYNMGAMGAA
SCHEMBL7523283 0.77 CA1 (0.56) CA1CA2FYNGAAALOX5
SCHEMBL19596581 0.74 CA1 (0.67) PDE4BEPHX2CA1CA2FYN
SCHEMBL9009416 0.73 EPHX2 (0.43) PDE4BEPHX2PDE4APDE4CPDE4D
SCHEMBL16808028 0.72 CA1 (0.42) PDE4BEPHX2CA1CA2FYN
SCHEMBL9571457 0.70 CA1 (0.59) CA1CA2FYNGAAALOX5
SCHEMBL5526665 0.69 CA1 (0.52) CA1CA2FYNGAAALOX5
SCHEMBL8959192 0.68 CA1 (0.41) PDE4BCA1CA2FYNPDE4A
SCHEMBL8895164 0.67 CA1 (0.54) CA1CA2FYNGAAALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0725053-B1 Selected O-quinonediazide sulfonic acid esters of phenolic compounds and their use in radiation-sensitive compositions OLIN MICROELECTRONIC CHEM INC (US) 2000-04-05 EP disclosed
EP-0840170-B1 Selected O-quinonediazide sulfonic acid esters of phenolic compounds OLIN MICROELECTRONIC CHEM INC (US) 2000-04-05 EP disclosed
EP-0840170-A1 Selected O-quinonediazide sulfonic acid esters of phenolic compounds OCG MICROELECTRONIC MATERIALS, INC. (US) 1998-05-06 EP disclosed
US-5602260-A PHOTORESISTS OCG MICROELECTRONIC MATERIALS, INC. (US) 1997-02-11 US disclosed
US-5547814-A PHOTORESISTS OCG MICROELECTRONIC MATERIALS, INC. (US) 1996-08-20 US disclosed
EP-0725053-A1 Selected O-quinonediazide sulfonic acid esters of phenolic compounds and their use in radiation-sensitive compositions OCG MICROELECTRONIC MATERIALS, INC. (US) 1996-08-07 EP disclosed
US-5541033-A PHOTOSENSITIVE COMPOUNDS FOR POSITIVE PHOTORESISTS FORMING PATTERNS OCG MICROELECTRONIC MATERIALS, INC. (US) 1996-07-30 US disclosed
US-5366843-A Coated substrate utilizing composition including selected phenolic derivatives of 4-(4-hydroxyphenyl)-cyclohexanone as sensitivity enhancers OCG MICROELECTRONIC MATERIALS, INC. (US) 1994-11-22 US disclosed
US-5346808-A Positive image formation utilizing o-quinonediazide composition including selected phenolic derivatives of 4-(4-hydroxyphenyl)-cyclohexanone OCG MICROELECTRONIC MATERIALS, INC. (US) 1994-09-13 US disclosed
US-5328806-A Positive image formation utilizing radiation sensitive mixture containing dimeric or trimeric sesamol/aldehyde condensation products as sensitivity enhancers OCG MICROELECTRONIC MATERIALS, INC. (US) 1994-07-12 US disclosed
US-5312720-A Development of photosensitive images exposed photoresists OCG MICROELECTRONIC MATERIALS INC. (US) 1994-05-17 US disclosed
US-5283374-A Selected phenolic derivatives of 4-(4-hydroxyphenyl)-cyclohexanone and their use as sensitivity enhancers for radiation sensitive mixtures OCG MICROELECTRONIC MATERIALS, INC. (US) 1994-02-01 US disclosed
US-5278021-A Photoactive compound OCG MICROELECTRONIC MATERIALS, INC. (US) 1994-01-11 US disclosed
US-5275911-A Sesamol/aldehyde condensation products as sensitivity enhancers for radiation sensitive mixtures OCG MICROELECTRONIC MATERIALS, INC. (US) 1994-01-04 US disclosed