Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.57 |
| ▸ | NPC1 | O15118 | 10/20 | 0.57 |
| ▸ | RAB9A | P51151 | 10/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | HTT | P42858 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043733 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AKDM4EKMT2A | |
| SCHEMBL4929465 | 0.78 | PAX8 (0.73) | SMN1; SMN2NPC1RAB9AKDM4EKMT2A | |
| SCHEMBL17190844 | 0.78 | KMT2A (0.78) | SMN1; SMN2NPC1RAB9AKDM4EKMT2A | |
| SCHEMBL29033679 | 0.78 | KMT2A (0.78) | SMN1; SMN2NPC1RAB9AKDM4EKMT2A | |
| SCHEMBL10143964 | 0.73 | RAB9A (1.00) | SMN1; SMN2NPC1RAB9AKDM4EKMT2A | |
| SCHEMBL29692738 | 0.73 | PAX8 (1.00) | SMN1; SMN2NPC1RAB9AKDM4EKMT2A | |
| SCHEMBL1164645 | 0.73 | PAX8 (1.00) | SMN1; SMN2NPC1RAB9AKDM4EKMT2A | |
| SCHEMBL4405365 | 0.73 | KMT2A (0.70) | SMN1; SMN2NPC1RAB9AKDM4EKMT2A | |
| SCHEMBL1164644 | 0.73 | PAX8 (1.00) | SMN1; SMN2NPC1RAB9AKDM4EKMT2A | |
| SCHEMBL1164949 | 0.71 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1RAB9AKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000103981-A | BIOTISSUE STAINING AGENT | AGENCY OF IND SCIENCE & TECHNOL | 2000-04-11 | — | — | JP | disclosed |