Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.48 |
| ▸ | RAB9A | P51151 | 12/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059348 | 0.83 | RAB9A (0.49) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8055131 | 0.77 | NPC1 (0.48) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL34467584 | 0.73 | NPC1 (0.63) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL240431 | 0.73 | NPC1 (0.63) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8061477 | 0.72 | NPC1 (0.44) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4337601 | 0.72 | NPC1 (0.61) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1370233 | 0.72 | ALDH1A1 (0.36) | NPC1RAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7759326 | 0.72 | RAB9A (0.63) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17449881 | 0.71 | RAB9A (0.62) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1102504 | 0.71 | RAB9A (0.66) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001959-A1 | METHOD FOR PRODUCING BIDENTATE MONOALKYL METAL COMPLEXES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999003867-A1 | METHOD FOR PRODUCING BIDENTATE MONOALKYL METAL COMPLEXES | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-28 | — | — | WO | disclosed |