Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098796 | 1.00 | GRM2 (0.37) | GRM2TSHRFFAR4SLC6A4SLC6A3 | |
| SCHEMBL8043882 | 0.96 | TSHR (0.39) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8043879 | 0.96 | TSHR (0.39) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8015349 | 0.90 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8015343 | 0.90 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8015344 | 0.90 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8083951 | 0.88 | JAK2 (0.33) | GRM2TSHRFFAR4SCN9AALOX5 | |
| SCHEMBL8083947 | 0.88 | JAK2 (0.33) | GRM2TSHRFFAR4SCN9AALOX5 | |
| SCHEMBL8096004 | 0.85 | MAOB (0.43) | — | |
| SCHEMBL8096006 | 0.85 | MAOB (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668286-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-12-20 | — | — | EP | disclosed |
| US-5523440-A | Silacyclohexane compound, a method of preparaing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0668286-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-08-23 | — | — | EP | disclosed |