Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | GRK6 | P43250 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032795 | 0.81 | HPGD (0.56) | KDM4EGRK6HPGDALDH1A1CYP1A2 | |
| SCHEMBL8043319 | 0.80 | KDM4E (0.53) | KDM4EGRK6HPGDALDH1A1CYP1A2 | |
| SCHEMBL8042216 | 0.78 | KDM4E (0.46) | KDM4EGRK6HPGDALDH1A1CYP1A2 | |
| SCHEMBL8044866 | 0.77 | GRK6 (0.62) | KDM4EGRK6HPGDALDH1A1CYP1A2 | |
| SCHEMBL8043421 | 0.76 | KDM4E (0.50) | KDM4EGRK6HPGDALDH1A1CYP1A2 | |
| SCHEMBL8042995 | 0.75 | KDM4E (0.49) | KDM4EGRK6HPGDALDH1A1CYP1A2 | |
| SCHEMBL8042483 | 0.75 | KDM4E (0.49) | KDM4EGRK6HPGDALDH1A1CYP1A2 | |
| SCHEMBL8048057 | 0.75 | RAB9A (0.39) | KDM4EHPGDALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8043204 | 0.74 | KDM4E (0.46) | KDM4EGRK6HPGDALDH1A1CYP1A2 | |
| SCHEMBL8032725 | 0.74 | PPARG (0.44) | KDM4EGRK6HPGDALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |