Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409285 | 0.95 | MAP3K7 (0.39) | TTRGAAKMT2AHSD17B10HDAC6 | |
| SCHEMBL8055374 | 0.94 | TTR (0.44) | TTRKMT2AALDH1A1TP53POLB | |
| SCHEMBL8043973 | 0.91 | HTT (0.40) | TTRGAAKMT2AHSD17B10HDAC6 | |
| SCHEMBL8409160 | 0.89 | TTR (0.40) | TTRKMT2ATP53LMNAPTGER4 | |
| SCHEMBL9408813 | 0.88 | NPC1 (0.40) | TTRKMT2AALDH1A1POLBLMNA | |
| SCHEMBL8406942 | 0.86 | MAP3K7 (0.39) | TTRGAAKMT2AHSD17B10HDAC6 | |
| SCHEMBL8043981 | 0.86 | NPC1 (0.50) | TTRGAAHDAC6HDAC2HDAC8 | |
| SCHEMBL8061708 | 0.84 | TTR (0.41) | TTRGAAKMT2AHDAC2ALDH1A1 | |
| SCHEMBL8043959 | 0.84 | HDAC6 (0.43) | TTRGAAHDAC6HDAC2HDAC8 | |
| SCHEMBL8061717 | 0.83 | TTR (0.42) | TTRGAAHDAC6HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826511-B1 | Heat sensitive recording material | OJI PAPER CO (JP) | 2000-05-24 | — | — | EP | disclosed |
| EP-0826511-A1 | Heat sensitive recording material | Oji Paper Co., Ltd. (JP) | 1998-03-04 | — | — | EP | disclosed |