Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055374 | 0.95 | TTR (0.44) | TTRHDAC1PTGER4SMN1; SMN2TP53 | |
| SCHEMBL8409285 | 0.92 | MAP3K7 (0.39) | TTRPTGER4SMN1; SMN2TP53MEN1 | |
| SCHEMBL8407973 | 0.91 | TTR (0.38) | TTRHDAC1MAPK8SMN1; SMN2RAB9A | |
| SCHEMBL8043958 | 0.89 | TTR (0.42) | TTRPTGER4SMN1; SMN2TP53RAB9A | |
| SCHEMBL8408952 | 0.87 | NPC1 (0.47) | TTRHDAC1MAPK8SMN1; SMN2TP53 | |
| SCHEMBL8061708 | 0.86 | TTR (0.41) | TTRHDAC1SMN1; SMN2TP53RAB9A | |
| SCHEMBL9408813 | 0.85 | NPC1 (0.40) | TTRPTGER4SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL8408950 | 0.85 | TTR (0.41) | TTRHDAC1MAPK8SMN1; SMN2RAB9A | |
| SCHEMBL8409167 | 0.84 | EPHX2 (0.49) | TTRMAPK8SMN1; SMN2RAB9AEPHX2 | |
| SCHEMBL8406942 | 0.84 | MAP3K7 (0.39) | TTREPHX2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935900-A | BENZOTRIAZOLE COMPOUND, DIPHENYLSULFONE ELECTRON ACCEPTOR | OJL PAPER CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |