Orcinol

Orcinol

SCHEMBL8043977

Cc1cc(O)cc(O)c1.Cc1ccc(N)cc1O

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 3/20 0.76
TSHR P16473 3/20 0.76
ALDH1A1 P00352 9/20 0.52
PDE10A Q9Y233 1/20 0.52
CYP3A4 P08684 4/20 0.42
RECQL P46063 1/20 0.40
ACHE P22303 1/20 0.39
TRPA1 O75762 1/20 0.39
PTGS1 P23219 1/20 0.39
CACNA1C Q13936 1/20 0.39
MAPT P10636 5/20 0.38
KDM4E B2RXH2 4/20 0.38
GAA P10253 3/20 0.38
CYP19A1 P11511 1/20 0.38
ESR2 Q92731 1/20 0.38
PTPN1 P18031 1/20 0.38
LMNA P02545 2/20 0.38
ALOX15 P16050 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4869221 0.87 CASP1 (1.00) CASP1TSHRALDH1A1PDE10ACYP3A4
SCHEMBL29670126 0.87
SCHEMBL93860 0.87
Resorcinol SCHEMBL8059792 0.84 TSHR (0.76) CASP1TSHRALDH1A1PDE10ACYP3A4
SCHEMBL5693266 0.81 ALDH1A1 (0.59) CASP1TSHRALDH1A1CYP3A4ACHE
Orcinol SCHEMBL6279994 0.81 ALDH1A1 (0.52) CASP1TSHRALDH1A1CYP3A4RECQL
Dimethylamine SCHEMBL9021118 0.81 CASP1 (0.86) CASP1TSHRALDH1A1PDE10ACYP3A4
Phenol SCHEMBL27557181 0.80 CASP1 (0.76) CASP1TSHRALDH1A1PDE10ACYP3A4
SCHEMBL10594028 0.79 CASP1 (0.83) CASP1TSHRALDH1A1PDE10ACYP3A4
3-Aminophenol SCHEMBL94098 0.78 CASP1 (0.73) CASP1TSHRALDH1A1PDE10ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1001734-A1 DYES Henkel Kommanditgesellschaft auf Aktien (DE) 2000-05-24 EP disclosed
WO-1999006016-A1 DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-02-11 WO disclosed