Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.44 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.44 |
| ▸ | RPS17 | P08708 | 1/20 | 0.44 |
| ▸ | RPSA | P08865 | 1/20 | 0.44 |
| ▸ | RPS2 | P15880 | 1/20 | 0.44 |
| ▸ | RPL35A | P18077 | 1/20 | 0.44 |
| ▸ | RPL7 | P18124 | 1/20 | 0.44 |
| ▸ | RPL17 | P18621 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211692 | 0.82 | L3MBTL1 (0.53) | ALDH1A1LMNASMN1; SMN2CYP3A4TSHR | |
| SCHEMBL14033751 | 0.79 | ALDH1A1 (0.53) | NPC1ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL8030913 | 0.79 | NPC1 (0.44) | NPC1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8915578 | 0.78 | MAPT (0.47) | NPC1ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL12159675 | 0.78 | ALDH1A1 (0.56) | NPC1ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL5657848 | 0.76 | KDM4E (0.48) | ALDH1A1LMNACYP3A4TSHRCYP2C19 | |
| SCHEMBL9969544 | 0.76 | ALDH1A1 (0.55) | NPC1ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| Propionic Acid SCHEMBL27773491 | 0.76 | ALDH1A1 (0.55) | NPC1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL10655753 | 0.76 | ALDH1A1 (0.55) | NPC1ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL10393558 | 0.76 | ALDH1A1 (0.53) | NPC1ALDH1A1LMNASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000015625-A2 | METHODS OF MAKING DIHYDROPYRONE HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | claimed |
| WO-2000015625-A2 | METHODS OF MAKING DIHYDROPYRONE HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |