Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885963 | 0.86 | EPHX1 (0.53) | CTRB1KMT2AMEN1TAAR1ALDH1A1 | |
| SCHEMBL27568996 | 0.86 | ALDH1A1 (0.46) | KMT2AMEN1TAAR1ALDH1A1HCAR2 | |
| SCHEMBL20804450 | 0.85 | FOLH1 (0.49) | KMT2AALDH1A1HCAR2MAPK1L3MBTL1 | |
| SCHEMBL27572427 | 0.84 | ALDH1A1 (0.50) | KMT2AALDH1A1HCAR2MAPK1L3MBTL1 | |
| SCHEMBL6128026 | 0.83 | CTRB1 (0.54) | CTRB1KMT2AALDH1A1HCAR2MAPK1 | |
| SCHEMBL6467419 | 0.82 | CTSK (0.55) | CTSB | |
| SCHEMBL27421029 | 0.82 | CTSK (0.55) | CTSB | |
| SCHEMBL27745748 | 0.82 | CTSK (0.55) | CTSB | |
| SCHEMBL8256369 | 0.82 | FOLH1 (0.53) | ALDH1A1TACR1ACE | |
| SCHEMBL4954521 | 0.81 | CTRB1 (0.52) | CTRB1KMT2AALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000074705-A1 | RHEUMATIC AUTOIMMUNE DISEASE ANTIGEN | PREHM PETER (DE) | 2000-12-14 | — | — | WO | disclosed |