Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15597194 | 0.88 | TDP1 (0.36) | ALDH1A1KDM4EGAAGLAMEN1 | |
| SCHEMBL8047377 | 0.86 | KMT2A (0.49) | ALDH1A1KDM4EGAAGLAMEN1 | |
| SCHEMBL8049631 | 0.83 | MEN1 (0.53) | ALDH1A1KDM4EGAAGLAMEN1 | |
| SCHEMBL18740421 | 0.82 | LMNA (0.51) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24815322 | 0.81 | ABL1 (0.43) | ALDH1A1KDM4EGAAGLAKMT2A | |
| SCHEMBL8052745 | 0.81 | AGTR1 (0.51) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL8044536 | 0.81 | NPC1 (0.44) | ALDH1A1KDM4EGAAGLAMEN1 | |
| SCHEMBL8053284 | 0.79 | MEN1 (0.51) | ALDH1A1KDM4EGAAGLAMEN1 | |
| SCHEMBL8045002 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAAGLAMEN1 | |
| SCHEMBL8035690 | 0.76 | PLAU (0.52) | ALDH1A1KDM4EMEN1KMT2AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789020-B1 | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL CO (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5780628-A | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0789020-A1 | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-13 | — | — | EP | disclosed |