Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629645 | 0.86 | POLB (0.42) | PIN1POLBPTGESMEN1KMT2A | |
| SCHEMBL27921821 | 0.83 | POLB (0.42) | PIN1POLBPTGESMEN1KMT2A | |
| SCHEMBL8044819 | 0.79 | TSHR (0.40) | RAB9AMAOBMAOAMAPTTDP1 | |
| SCHEMBL8031159 | 0.78 | PIN1 (0.48) | PIN1POLBMEN1KMT2ANPC1 | |
| SCHEMBL629877 | 0.75 | POLB (0.55) | PIN1POLBMEN1KMT2ANPC1 | |
| SCHEMBL27940470 | 0.74 | DHODH (0.44) | POLBMAOBMAOAMAPTMGMT | |
| SCHEMBL6178097 | 0.71 | PIN1 (0.49) | PIN1POLBPTGESMEN1KMT2A | |
| SCHEMBL27388637 | 0.70 | HTR1A (0.55) | PIN1POLBMEN1KMT2ANPC1 | |
| SCHEMBL4928212 | 0.70 | MAPT (0.55) | PIN1POLBMEN1KMT2ANPC1 | |
| SCHEMBL8041772 | 0.70 | HPGD (0.39) | POLBMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686144-B1 | NEW COMPOUNDS | UNIV MARYLAND (US) | 2000-04-19 | — | — | EP | disclosed |
| US-5688945-A | Compounds | ASTRA AKTIEBOLAG (SE) | 1997-11-18 | — | — | US | disclosed |
| US-5661183-A | 3-hydroxy anthanilic acid derivatives | THE UNIVERSITY OF MARYLAND (US) | 1997-08-26 | — | — | US | disclosed |
| EP-0686144-A1 | NEW COMPOUNDS | Astra Aktiebolag (SE) | 1995-12-13 | — | — | EP | disclosed |
| WO-1994019315-A1 | NEW COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1994-09-01 | — | — | WO | disclosed |