Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | USP8 | P40818 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888043 | 0.82 | AR (0.47) | NPC1RAB9AARSQORLMNA | |
| SCHEMBL7864724 | 0.81 | ALDH1A1 (0.44) | FDPSARMAPTGAAPOLB | |
| SCHEMBL3807595 | 0.81 | NPC1 (0.44) | FDPSNPC1RAB9AARSQOR | |
| SCHEMBL1154627 | 0.81 | SQOR (0.45) | NPC1RAB9AARSQORLMNA | |
| SCHEMBL3821367 | 0.81 | NPC1 (0.44) | FDPSNPC1RAB9AARSQOR | |
| SCHEMBL8623713 | 0.80 | NCF1 (0.40) | FDPSNPC1RAB9ALMNAMAPT | |
| SCHEMBL7050071 | 0.79 | HPGD (0.46) | ARLMNAMAPTCYP2C9GAA | |
| SCHEMBL29837403 | 0.79 | HPGD (0.46) | ARLMNAMAPTCYP2C9GAA | |
| SCHEMBL25233862 | 0.78 | SQOR (0.38) | FDPSNPC1RAB9AARSQOR | |
| SCHEMBL16982292 | 0.78 | AR (0.50) | NPC1RAB9AARSQORLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558449-B1 | Complexes of chelating ligands and process for their preparation | NOVARTIS AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| US-5686439-A | Chelate complexes and processes for their preparation | NOVARTIS CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
| US-5670491-A | Chelate complexes and processes for their preparation | CIBA-GEIGY CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |
| US-5358940-A | Chelate complexes and processes for their preparation | CIBA-GEIGY CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0558449-A1 | Complexes of chelating ligands and process for their preparation | CIBA-GEIGY AG (CH) | 1993-09-01 | — | — | EP | disclosed |