Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409577 | 0.86 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAHTTKEAP1 | |
| SCHEMBL29971140 | 0.86 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAHTTKEAP1 | |
| SCHEMBL875676 | 0.85 | BCL2 (0.54) | KDM4EALDH1A1SMN1; SMN2BCL2BCL2L1 | |
| SCHEMBL2580758 | 0.79 | ALOX5 (0.49) | ALDH1A1SMN1; SMN2ALOX5CALM1LMNA | |
| SCHEMBL27657488 | 0.78 | IDH1 (0.58) | KDM4ESMN1; SMN2BCL2BCL2L1ALOX5 | |
| SCHEMBL1838403 | 0.78 | BCL2 (0.57) | BCL2BCL2L1ALOX5IDH1CALM1 | |
| SCHEMBL11213120 | 0.78 | HSPA5 (0.54) | BCL2BCL2L1ALOX5IDH1CALM1 | |
| SCHEMBL30957380 | 0.78 | BCL2 (0.57) | BCL2BCL2L1ALOX5IDH1CALM1 | |
| SCHEMBL560292 | 0.76 | ALDH1A1 (0.48) | ALDH1A1BCL2BCL2L1ALOX5IDH1 | |
| SCHEMBL7647682 | 0.76 | BCL2 (0.50) | BCL2BCL2L1ALOX5IDH1CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606858-B1 | Liquid crystal compositions and liquid crystal display devices | CHISSO CORP (JP) | 2000-04-26 | — | — | EP | claimed |
| EP-0606858-A1 | Liquid crystal compositions and liquid crystal display devices | CHISSO CORPORATION (JP) | 1994-07-20 | — | — | EP | claimed |
| US-4060562-A | SULFUR CONTAINING CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-29 | — | — | US | disclosed |