Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046351 | 0.86 | NPC1 (0.51) | NAMPTHDAC3HTR1AHTR1DDRD4 | |
| SCHEMBL8045257 | 0.85 | NAMPT (0.55) | NAMPTHDAC3HTR1AHTR1DROCK2 | |
| SCHEMBL8035576 | 0.85 | HPGD (0.47) | NAMPTHDAC3HTR1AHTR1D | |
| SCHEMBL8050562 | 0.85 | NAMPT (0.57) | NAMPTGAADRD4DRD2 | |
| SCHEMBL8035856 | 0.85 | NAMPT (0.50) | NAMPTHDAC3HTR1AHTR1DDRD4 | |
| Hydrochloric Acid SCHEMBL8152540 | 0.85 | NPC1 (0.50) | NAMPTHDAC3HTR1AHTR1DDRD4 | |
| SCHEMBL8045277 | 0.83 | NPC1 (0.51) | NAMPTHDAC3HTR1AHTR1D | |
| SCHEMBL8048246 | 0.83 | NAMPT (0.57) | NAMPTHDAC3HTR1AHTR1DDRD2 | |
| SCHEMBL8655180 | 0.82 | HDAC3 (0.52) | HDAC3DRD4DRD2DRD3 | |
| SCHEMBL8036163 | 0.82 | ALDH1A1 (0.53) | HDAC3ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679649-B1 | 2,3-Dihydrobenzofuran Derivatives | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | claimed |
| EP-0679649-B1 | 2,3-Dihydrobenzofuran Derivatives | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| EP-0679649-A1 | 2,3-DIHYDROBENZOFURAN DERIVATIVE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-11-02 | — | — | EP | disclosed |