⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045506 | 1.00 | — | — | |
| SCHEMBL8049312 | 0.81 | — | — | |
| SCHEMBL8052225 | 0.75 | — | — | |
| SCHEMBL8034833 | 0.70 | — | — | |
| SCHEMBL8035154 | 0.67 | NOS3 (0.31) | — | |
| SCHEMBL8034842 | 0.67 | — | — | |
| SCHEMBL8052716 | 0.61 | NISCH (0.40) | — | |
| SCHEMBL8046830 | 0.60 | ALOX15 (0.33) | — | |
| SCHEMBL17375464 | 0.57 | — | — | |
| SCHEMBL9155391 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661290-B1 | Compounds containing 1-aza-3-oxa-4-silacyclohex-1-enyl groups, and tautomers of said compounds | DOW CORNING ASIA LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5446180-A | Compounds containing 1-aza-3-oxa-4-silacyclohex-1-enyl groups, and tautomers of said compounds | DOW CORNING ASIA LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0661290-A1 | Compounds containing 1-aza-3-oxa-4-silacyclohex-1-enyl groups, and tautomers of said compounds | DOW CORNING ASIA, Ltd. (JP) | 1995-07-05 | — | — | EP | disclosed |