Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 3/20 | 0.71 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028846 | 0.83 | GLO1 (1.00) | GLO1GPR35CA1CA2CA4 | |
| SCHEMBL7245950 | 0.81 | GLO1 (0.66) | GLO1GPR35ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8028708 | 0.79 | GPR35 (0.85) | GLO1GPR35ALDH1A1KDM4EMEN1 | |
| SCHEMBL9401844 | 0.76 | GLO1 (0.86) | GLO1CA1CA2CA4CA7 | |
| SCHEMBL7277503 | 0.76 | GLO1 (0.86) | GLO1CA1CA2CA4CA7 | |
| SCHEMBL7271725 | 0.76 | GLO1 (0.86) | GLO1CA1CA2CA4CA7 | |
| SCHEMBL7271722 | 0.76 | GLO1 (0.86) | GLO1CA1CA2CA4CA7 | |
| Nitecapone SCHEMBL7039409 | 0.75 | GPR35 (1.00) | GLO1GPR35ALDH1A1MEN1LMNA | |
| Nitecapone SCHEMBL128420 | 0.75 | GPR35 (1.00) | GLO1GPR35ALDH1A1MEN1LMNA | |
| Nitecapone SCHEMBL30489171 | 0.75 | GPR35 (1.00) | GLO1GPR35ALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440324-A2 | Substituted beta-diketones and their use | ORION-YHTYMÀ OY (FI) | 1991-08-07 | — | — | EP | claimed |
| EP-0440324-B1 | Substituted beta-diketones and their use in the treatment of inflammatory bowel disease | ORION YHTYMAE OY (FI) | 2000-04-12 | — | — | EP | disclosed |
| US-5292771-A | Treating inflammatory bowel disease | ORION-YHTYMA OY (FI) | 1994-03-08 | — | — | US | disclosed |
| US-5185370-A | Substituted β-diketones and their use | ORION-YHTYMA OY (FI) | 1993-02-09 | — | — | US | disclosed |
| EP-0440324-A2 | Substituted beta-diketones and their use | ORION-YHTYMÀ OY (FI) | 1991-08-07 | — | — | EP | disclosed |