Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.50 |
| ▸ | METAP1 | P53582 | 4/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045875 | 0.83 | SMN1; SMN2 (0.51) | ACHECYP19A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL2187398 | 0.72 | ACHE (0.47) | ACHEMETAP1CYP19A1SMN1; SMN2NPC1 | |
| SCHEMBL5667503 | 0.72 | ACHE (0.51) | ACHEMETAP1CYP19A1TSHRSMN1; SMN2 | |
| SCHEMBL7344411 | 0.71 | PYGL (0.49) | NPC1MAPTDRD2 | |
| SCHEMBL8797208 | 0.70 | ACHE (0.49) | ACHEMETAP1CYP19A1TSHRSMN1; SMN2 | |
| SCHEMBL16795631 | 0.70 | ACHE (0.51) | ACHEMETAP1CYP19A1TSHR | |
| SCHEMBL10947753 | 0.70 | ACHE (0.49) | ACHEMETAP1CYP19A1TSHRSMN1; SMN2 | |
| SCHEMBL10947764 | 0.70 | ACHE (0.49) | ACHEMETAP1CYP19A1TSHRSMN1; SMN2 | |
| SCHEMBL14157895 | 0.70 | ACHE (0.63) | ACHEMETAP1CYP19A1TSHRSMN1; SMN2 | |
| SCHEMBL5539639 | 0.70 | ACHE (0.63) | ACHEMETAP1CYP19A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991772-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS | Biocatalytics, Inc. (US) | 2000-04-12 | — | — | EP | disclosed |
| US-5942644-A | Precursors for the production of chiral vicinal aminoalcohols | BIOCATALYTICS, INC. (US) | 1999-08-24 | — | — | US | disclosed |
| WO-1998054350-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS | BIOCATALYTICS, INC. (US) | 1998-12-03 | — | — | WO | disclosed |