Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035997 | 0.67 | ALDH1A1 (0.37) | KDM4EMEN1KMT2ALMNA | |
| SCHEMBL11683149 | 0.64 | LMNA (0.40) | TDP2KDM4EDUSP3MEN1KMT2A | |
| SCHEMBL7521891 | 0.60 | HPGD (0.36) | KDM4EMEN1KMT2A | |
| SCHEMBL28149046 | 0.60 | KDM4E (0.37) | TDP2KDM4EDUSP3MEN1KMT2A | |
| SCHEMBL27523171 | 0.60 | KDM4E (0.37) | TDP2KDM4EDUSP3MEN1KMT2A | |
| SCHEMBL4983780 | 0.59 | ADRB2 (0.55) | — | |
| SCHEMBL22509324 | 0.59 | SERPINE1 (0.46) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL22509325 | 0.59 | ALDH1A1 (0.41) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL13381403 | 0.59 | ADRB2 (0.44) | TDP2KDM4EDUSP3MEN1KMT2A | |
| SCHEMBL10647531 | 0.58 | KDM4E (0.35) | TDP2KDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832054-B1 | HETEROCYCLIC METHYL FREE RADICALS AS IMAGE ENHANCING AGENTS | NYCOMED IMAGING AS (NO) | 2000-12-27 | — | — | EP | disclosed |
| US-6063360-A | USEFUL AS CONTRAST AGENT FOR OVERHAUSER MAGNETIC RESONACE IMAGING | NYCOMED IMAGING A/S (NO) | 2000-05-16 | — | — | US | disclosed |
| WO-1996039367-A1 | HETEROCYCLIC METHYL FREE RADICALS AS IMAGE ENHANCING AGENTS | NYCOMED IMAGING A/S (NO) | 1996-12-12 | — | — | WO | disclosed |
| US-5530140-A | Free radicals | NYCOMED IMAGING AS (NO) | 1996-06-25 | — | — | US | disclosed |