Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 2/20 | 0.40 |
| ▸ | MLYCD | O95822 | 4/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 11/20 | 0.36 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207340 | 0.74 | HPGD (0.51) | F2F10F7MLYCDLPAR1 | |
| SCHEMBL12687787 | 0.71 | MLYCD (0.44) | F2F10F7MLYCDLPAR1 | |
| SCHEMBL12156556 | 0.70 | MLYCD (0.43) | F2F10F7MLYCDLPAR1 | |
| SCHEMBL10460373 | 0.70 | MLYCD (0.48) | F2F10F7MLYCDLPAR1 | |
| SCHEMBL13034663 | 0.69 | F2 (0.36) | F2F10F7MLYCDLPAR1 | |
| SCHEMBL12465682 | 0.69 | MLYCD (0.42) | F2F10F7MLYCDLPAR1 | |
| SCHEMBL3041802 | 0.69 | GABRP (0.47) | F2F10F7MLYCDLPAR1 | |
| SCHEMBL3044303 | 0.68 | LPAR1 (0.36) | F2F10F7MLYCDLPAR1 | |
| Bromide SCHEMBL3044300 | 0.68 | LPAR1 (0.36) | F2F10F7LPAR1LPAR5 | |
| SCHEMBL8806252 | 0.67 | HPGD (0.47) | F2F10F7MLYCDLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034500-A1 | SUBSTITUTED IMIDAZOPYRIDINE, IMIDAZOPYRAZINE, IMIDAZOPYRIDAZINE AND IMIDAZOPYRIMIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR ANTAGONISTS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2010-04-01 | — | — | WO | disclosed |
| EP-2168965-A1 | Substituted imidazopyridine, imidazopyrazine, imidazopyridazine and imidazopyrimidine derivatives as melanocortin-4 receptor antagonists | Santhera Pharmaceuticals (Schweiz) AG (CH) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009080291-A1 | SUBSTITUTED IMIDAZOPYRIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR ANTAGONISTS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2009-07-02 | — | — | WO | disclosed |