SCHEMBL8045826

SCHEMBL8045826

O=CN(SCl)C1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 12/20 0.48
ADH1C P00326 9/20 0.46
ADH4 P08319 3/20 0.44
ADH1B P00325 3/20 0.42
PHGDH O43175 1/20 0.31
ADH7 P40394 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11855614 0.81 ADH1A (0.52) ADH1AADH1CADH4ADH1BPHGDH
SCHEMBL4854252 0.77 ADH1A (0.43) ADH1AADH1CADH4ADH1BPHGDH
SCHEMBL11853298 0.72 ADH1A (0.39) ADH1AADH1CADH4ADH1B
SCHEMBL11701953 0.69 ADH1A (0.54) ADH1AADH1CADH4ADH1BPHGDH
SCHEMBL10913207 0.67 ADH1A (0.94) ADH1AADH1CADH4ADH1BPHGDH
SCHEMBL10013014 0.67 ADH1A (0.94) ADH1AADH1CADH4ADH1BPHGDH
SCHEMBL14855293 0.67 ADH1A (0.94) ADH1AADH1CADH4ADH1BPHGDH
SCHEMBL39255 0.67 ADH1A (0.94) ADH1AADH1CADH4ADH1BPHGDH
SCHEMBL10012570 0.67 ADH1A (0.94) ADH1AADH1CADH4ADH1BPHGDH
SCHEMBL8745531 0.67 ADH1A (0.94) ADH1AADH1CADH4ADH1BPHGDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4017468-A IMIDE-MODIFIED TERPOLYMERSSULFUR-CURED RUBBER, TIRES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-04-12 US claimed
US-3997605-A Preparation of formamide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-12-14 US claimed
EP-0989171-A1 N-halothio-amide-modified elastomers and their application as adhesives for precured elastomeric substrates THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-03-29 EP disclosed
US-4017468-A IMIDE-MODIFIED TERPOLYMERSSULFUR-CURED RUBBER, TIRES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-04-12 US disclosed
US-3997605-A Preparation of formamide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-12-14 US disclosed
US-3997605-A Preparation of formamide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-12-14 US disclosed