Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 10/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | ADH1C | P00326 | 7/20 | 0.42 |
| ▸ | ADH4 | P08319 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045826 | 0.77 | ADH1A (0.48) | ADH1AADH1CADH4ADH1BPHGDH | |
| SCHEMBL11855614 | 0.76 | ADH1A (0.52) | ADH1AFDPSADH1CADH4ADH1B | |
| SCHEMBL11853298 | 0.68 | ADH1A (0.39) | ADH1AADH1CADH4ADH1B | |
| Phosphoric Acid SCHEMBL28334275 | 0.66 | FDPS (0.54) | ADH1AFDPSADH1CADH4ADH1B | |
| SCHEMBL3075520 | 0.65 | FDPS (0.44) | ADH1AFDPSADH1CALDH1A1PHGDH | |
| SCHEMBL6687189 | 0.64 | FDPS (0.52) | ADH1AFDPSADH1CADH4ADH1B | |
| SCHEMBL11701953 | 0.64 | ADH1A (0.54) | ADH1AFDPSADH1CADH4ADH1B | |
| SCHEMBL3068146 | 0.64 | FDPS (0.52) | ADH1AFDPSADH1CADH4ADH1B | |
| SCHEMBL8905856 | 0.64 | ADH1A (0.54) | ADH1AFDPSADH1CADH4ADH1B | |
| SCHEMBL8573220 | 0.64 | FDPS (0.47) | ADH1AFDPSADH1CADH4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7468359-B2 | Compositions comprising oxophosphonate-based metalloproteinase inhibitors | YISSUM RESEARCH DEVELPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (US) | 2008-12-23 | — | — | US | disclosed |
| US-20060199787-A1 | COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-09-07 | — | — | US | disclosed |
| US-7101864-B1 | Compositions comprising oxophosphonate-based metalloproteinase inhibitors | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-09-05 | — | — | US | disclosed |
| EP-1223945-A1 | COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001026661-A1 | COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199787-A1 | COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS | ENPP1, MMP1, MMP9 | ADH1A 3388/4885FDPS 402/4885ADH1C 3563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.