Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575920 | 0.87 | MAPT (0.58) | MAPTNPC1RAB9AMAPK1LMNA | |
| SCHEMBL8387178 | 0.84 | MAPT (0.60) | MAPTKMT2ANPC1MEN1RAB9A | |
| SCHEMBL32672129 | 0.84 | MAPT (0.60) | MAPTKMT2ANPC1MEN1RAB9A | |
| SCHEMBL690306 | 0.82 | KMT2A (0.54) | MAPTKMT2AMEN1ABCG2KDM4E | |
| SCHEMBL28716841 | 0.82 | KMT2A (0.57) | MAPTKMT2ANPC1MEN1RAB9A | |
| SCHEMBL9211658 | 0.82 | MAPT (0.68) | MAPTKMT2ANPC1MEN1RAB9A | |
| SCHEMBL27812148 | 0.80 | MAPT (0.67) | MAPTKMT2ANPC1MEN1RAB9A | |
| SCHEMBL28968013 | 0.80 | MAPT (0.67) | MAPTKMT2ANPC1MEN1RAB9A | |
| SCHEMBL16628764 | 0.80 | KMT2A (0.57) | MAPTKMT2ANPC1MEN1RAB9A | |
| SCHEMBL30205105 | 0.80 | NPC1 (0.81) | MAPTKMT2ANPC1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165449-A | Methods and compositions for improving sun protection from sunscreen formulations | STEPAN COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
| US-5939046-A | ASSESSING AN IMMUNE RESPONSE OF THE SKIN OF AT LEAST ONE MAMMAL TO AN ANTIGEN | HALLIDAY GARY M (AU) | 1999-08-17 | — | — | US | disclosed |