Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051692 | 0.88 | KDM4E (0.38) | MEN1KMT2AKDM4ETSHRNPC1 | |
| SCHEMBL8044858 | 0.87 | TSHR (0.49) | MEN1KMT2AKDM4ETSHRNPC1 | |
| SCHEMBL8051653 | 0.85 | TSHR (0.41) | MEN1KMT2AKDM4ETSHRNPC1 | |
| SCHEMBL8051906 | 0.84 | RAB9A (0.45) | MEN1KMT2AKDM4ETSHRNPC1 | |
| SCHEMBL8046882 | 0.83 | RECQL (0.41) | MEN1KMT2AKDM4ETSHRNPC1 | |
| SCHEMBL8051552 | 0.83 | KDM4E (0.53) | MEN1KMT2AKDM4ETSHRNPC1 | |
| SCHEMBL8045332 | 0.83 | NPC1 (0.46) | MEN1KMT2AKDM4ETSHRNPC1 | |
| SCHEMBL8044774 | 0.80 | KDM4E (0.43) | MEN1KMT2AKDM4ETSHRNPC1 | |
| SCHEMBL8044738 | 0.79 | CSNK1D (0.39) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL8042759 | 0.78 | NPC1 (0.43) | MEN1KMT2AKDM4ETSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |