Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ILK | Q13418 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042112 | 0.88 | CSNK1D (0.39) | CSNK1DKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8044044 | 0.88 | KMT2A (0.45) | CSNK1DKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8043389 | 0.86 | PDK1 (0.44) | KMT2ASMN1; SMN2MEN1ALDH1A1USP2 | |
| SCHEMBL8046372 | 0.86 | RAB9A (0.41) | CSNK1DKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8034281 | 0.85 | KMT2A (0.40) | KMT2ASMN1; SMN2MEN1ALDH1A1USP2 | |
| SCHEMBL8043400 | 0.85 | ALDH1A1 (0.53) | KMT2ASMN1; SMN2MEN1ALDH1A1USP2 | |
| SCHEMBL8044955 | 0.85 | USP2 (0.48) | CSNK1DKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8051920 | 0.80 | TSHR (0.51) | CSNK1DKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8044199 | 0.80 | TSHR (0.41) | CSNK1DKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8045950 | 0.79 | MEN1 (0.38) | KMT2ASMN1; SMN2MEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |