Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048230 | 0.85 | KDM4E (0.43) | KDM4ENPC1RAB9ATSHRMEN1 | |
| SCHEMBL8045928 | 0.85 | TSHR (0.52) | KDM4ENPC1RAB9ATSHRMEN1 | |
| SCHEMBL8051653 | 0.83 | TSHR (0.41) | KDM4ENPC1RAB9ATSHRMEN1 | |
| SCHEMBL8044904 | 0.81 | TSHR (0.41) | KDM4ENPC1RAB9ATSHRMEN1 | |
| SCHEMBL8050300 | 0.81 | KDM4E (0.40) | KDM4ENPC1RAB9ATSHRMEN1 | |
| SCHEMBL8043400 | 0.81 | ALDH1A1 (0.53) | KDM4EHTR7NPC1RAB9ATSHR | |
| SCHEMBL8050800 | 0.81 | HTR1A (0.49) | KDM4EHTR7NPC1RAB9ATSHR | |
| SCHEMBL8045950 | 0.80 | MEN1 (0.38) | KDM4ENPC1RAB9ATSHRMEN1 | |
| SCHEMBL8046882 | 0.80 | RECQL (0.41) | KDM4ENPC1RAB9ATSHRMEN1 | |
| SCHEMBL8042512 | 0.80 | RAB9A (0.50) | KDM4ENPC1RAB9ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |