Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039152 | 0.87 | APP (0.44) | APPDRD2GRM3CHRM2CHRM1 | |
| SCHEMBL13621706 | 0.84 | DRD2 (0.50) | APPDRD2GRM3ACACBESR2 | |
| SCHEMBL5343187 | 0.84 | DRD2 (0.50) | APPDRD2GRM3ACACBESR2 | |
| SCHEMBL9509006 | 0.82 | DRD2 (0.48) | APPDRD2GRM3ESR2 | |
| SCHEMBL8040016 | 0.81 | DRD2 (0.43) | APPDRD2GRM3CHRM2CHRM1 | |
| SCHEMBL9512333 | 0.81 | DRD2 (0.49) | APPDRD2GRM3ACACBGRM2 | |
| SCHEMBL9509299 | 0.81 | DRD2 (0.47) | APPDRD2GRM3 | |
| SCHEMBL9508804 | 0.81 | DRD2 (0.47) | APPDRD2GRM3GRM2 | |
| SCHEMBL26347319 | 0.81 | DRD2 (0.47) | APPDRD2GRM3GRM2 | |
| SCHEMBL9511758 | 0.80 | DRD2 (0.46) | APPDRD2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |