Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26347319 | 1.00 | DRD2 (0.47) | DRD2CYP2C9APPMEN1KMT2A | |
| SCHEMBL9511758 | 0.99 | DRD2 (0.46) | DRD2CYP2C9APPMEN1KMT2A | |
| SCHEMBL9509006 | 0.96 | DRD2 (0.48) | DRD2CYP2C9APPMEN1KMT2A | |
| SCHEMBL9509338 | 0.92 | DRD2 (0.45) | DRD2CYP2C9APPMEN1KMT2A | |
| SCHEMBL7910586 | 0.92 | DRD2 (0.54) | DRD2CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL7910589 | 0.92 | DRD2 (0.54) | DRD2CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL9512219 | 0.91 | RAB9A (0.47) | CYP2C9LMNARAB9A | |
| SCHEMBL5343187 | 0.91 | DRD2 (0.50) | DRD2CYP2C9APPMEN1KMT2A | |
| SCHEMBL13621706 | 0.91 | DRD2 (0.50) | DRD2CYP2C9APPMEN1KMT2A | |
| SCHEMBL9744172 | 0.91 | SLC6A2 (0.39) | DRD2CYP2C9MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |