Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047964 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL8034048 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL8044462 | 0.79 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL8042813 | 0.79 | KDM4E (0.52) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL8043598 | 0.79 | RECQL (0.55) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL8052083 | 0.79 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL8033946 | 0.78 | ATM (0.45) | ALDH1A1SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL8042821 | 0.77 | RPA1 (0.54) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL8050649 | 0.77 | RECQL (0.37) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL8050065 | 0.77 | KDM4E (0.52) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |