Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043598 | 0.82 | RECQL (0.55) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL8051302 | 0.82 | ATM (0.48) | ATMSMN1; SMN2HTTPOLBMEN1 | |
| SCHEMBL8032636 | 0.81 | ATM (0.47) | ATMSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL8042821 | 0.79 | RPA1 (0.54) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL8050649 | 0.79 | RECQL (0.37) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8045955 | 0.78 | RXRA (0.39) | POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL8046541 | 0.78 | KDM4E (0.47) | SMN1; SMN2L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL8047690 | 0.77 | SMN1; SMN2 (0.50) | ATMSMN1; SMN2HTTPOLBMEN1 | |
| SCHEMBL8043910 | 0.76 | ALPG (0.46) | SMN1; SMN2HTTPOLBMEN1KMT2A | |
| SCHEMBL8050081 | 0.76 | TSHR (0.48) | ATMSMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |