Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.31 |
| ▸ | VCP | P55072 | 3/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050859 | 0.89 | ALDH1A1 (0.35) | ALDH1A1KMT2AHTTMEN1MAPT | |
| SCHEMBL8043099 | 0.82 | TSHR (0.57) | ALDH1A1KMT2AHTTMEN1MAPT | |
| SCHEMBL8043571 | 0.82 | ATM (0.43) | ALDH1A1KMT2AHTTMEN1TSHR | |
| SCHEMBL8716255 | 0.81 | TP53 (0.43) | ALDH1A1KMT2AHTTMEN1RAB9A | |
| SCHEMBL8042649 | 0.80 | ALDH1A1 (0.36) | ALDH1A1KMT2AHTTMEN1MAPT | |
| SCHEMBL8044131 | 0.80 | RPA1 (0.44) | ALDH1A1KMT2AHTTMEN1MAPT | |
| SCHEMBL8050718 | 0.80 | HTT (0.51) | ALDH1A1KMT2AHTTMEN1MAPT | |
| SCHEMBL8043752 | 0.79 | KDM4E (0.48) | ALDH1A1KMT2AHTTMEN1MAPT | |
| SCHEMBL8043561 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KMT2AHTTMAPTRAB9A | |
| SCHEMBL8044820 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |