Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 3/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061803 | 0.92 | ALDH1A1 (0.53) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8059188 | 0.91 | ALDH1A1 (0.54) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8064228 | 0.88 | ALDH1A1 (0.52) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL27513354 | 0.85 | ALDH1A1 (0.55) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10401157 | 0.85 | KDM4E (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8058512 | 0.84 | ALDH1A1 (0.52) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10401294 | 0.83 | TOP2A (0.62) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8061575 | 0.82 | TOP2A (0.50) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8058565 | 0.81 | KDM4E (0.52) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10401477 | 0.79 | ALDH1A1 (0.76) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034086-A | VIRICIDES; AIDS THERAPY | UBE INDUSTRIES, LTD. | 2000-03-07 | — | — | US | disclosed |
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |
| CN-1152916-A | Trifluoromethylquinoline carboxylic acid derivative | UBE INDUSTRIES (JP) | 1997-06-25 | — | — | CN | disclosed |
| EP-0773214-A1 | TRIFLUOROMETHYLQUINOLINECARBOXYLIC ACID DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |