Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906819 | 0.85 | AR (0.43) | ARSLC22A12KDM4EALDH1A1GAA | |
| SCHEMBL18352625 | 0.80 | ALDH1A1 (0.54) | ARKDM4EALDH1A1GAAMAPT | |
| SCHEMBL2285228 | 0.78 | ALDH1A1 (0.50) | ARKDM4EALDH1A1GAAMAPT | |
| SCHEMBL646513 | 0.78 | L3MBTL1 (0.44) | ARPGRSLC22A12KDM4EALDH1A1 | |
| SCHEMBL7868327 | 0.78 | AR (0.46) | ARPGRSLC22A12 | |
| SCHEMBL1275083 | 0.76 | SLC22A12 (0.55) | ARSLC22A12KDM4EALDH1A1GAA | |
| SCHEMBL18190631 | 0.76 | CA1 (0.39) | ARSLC22A12KDM4EALDH1A1GAA | |
| SCHEMBL2417258 | 0.76 | CUL4A (0.46) | ARSLC22A12KDM4EALDH1A1GAA | |
| SCHEMBL8118463 | 0.76 | AR (0.46) | ARSLC22A12KDM4EALDH1A1GAA | |
| SCHEMBL1409424 | 0.76 | AR (0.37) | ARSLC22A12KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606858-B1 | Liquid crystal compositions and liquid crystal display devices | CHISSO CORP (JP) | 2000-04-26 | — | — | EP | claimed |
| US-5985170-A | OF SUPERTWISTED NEMATIC (STN) MODE, CYANOPHENOL, (TRIFLUOROMETHYL)CYANOPHENOL, AND CYANODIFLUOROPHENOL, CONTROLLING A VOLTAGE HOLDING RATIO | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | claimed |
| EP-0606858-A1 | Liquid crystal compositions and liquid crystal display devices | CHISSO CORPORATION (JP) | 1994-07-20 | — | — | EP | claimed |
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-0606858-B1 | Liquid crystal compositions and liquid crystal display devices | CHISSO CORP (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5985170-A | OF SUPERTWISTED NEMATIC (STN) MODE, CYANOPHENOL, (TRIFLUOROMETHYL)CYANOPHENOL, AND CYANODIFLUOROPHENOL, CONTROLLING A VOLTAGE HOLDING RATIO | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5723065-A | CONDENSED HETEROCYCLE AND AROMATIC AMINE, ALIPHATIC AMINE AND FLUOROCYANOPHENOL | CHISSO CORPORATION (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0606858-A1 | Liquid crystal compositions and liquid crystal display devices | CHISSO CORPORATION (JP) | 1994-07-20 | — | — | EP | disclosed |