Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049854 | 0.85 | MAOB (0.38) | MAOB | |
| SCHEMBL8047757 | 0.85 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL8052536 | 0.83 | MAOB (0.40) | MAOB | |
| SCHEMBL8048836 | 0.83 | GRIA1 (0.33) | — | |
| SCHEMBL8049101 | 0.83 | THRB (0.34) | — | |
| SCHEMBL9351035 | 0.81 | MAOA (0.39) | MAOAMAOBHRH3KCNJ1KCNH2 | |
| SCHEMBL9351042 | 0.81 | MAOA (0.39) | MAOAMAOBHRH3KCNJ1KCNH2 | |
| SCHEMBL8037733 | 0.81 | TEAD1 (0.34) | BACE1 | |
| SCHEMBL8049022 | 0.80 | HRH3 (0.33) | HRH3KCNH2 | |
| SCHEMBL8055273 | 0.80 | TBXA2R (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728829-B1 | Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-5698136-A | LOW TEMPERATURE COMPATIBILITY, CHEMICAL STABILITY | CHISSO CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0728829-A2 | Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1996-08-28 | — | — | EP | disclosed |