Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.35 |
| ▸ | S100B | P04271 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4863422 | 0.94 | ALDH1A1 (0.73) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL4858474 | 0.92 | ALDH1A1 (0.71) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL4862764 | 0.92 | ALDH1A1 (0.71) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| Hydrochloric Acid SCHEMBL4854566 | 0.91 | ALDH1A1 (0.69) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| Hydrochloric Acid SCHEMBL4854362 | 0.91 | ALDH1A1 (0.69) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| Sulfuric Acid SCHEMBL6658121 | 0.91 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| Sulfuric Acid SCHEMBL8751386 | 0.90 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL4858416 | 0.89 | ALDH1A1 (0.65) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL2933227 | 0.86 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL6369975 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TDP1THRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595312-B1 | Automatic processing machine for silver halide photographic light-sensitive materials | KONISHIROKU PHOTO IND (JP) | 2000-04-19 | — | — | EP | disclosed |
| EP-0854386-A2 | Automatic processing machine for silver halide photographic light-sensitive materials | KONICA CORPORATION (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5663039-A | AT LEAST A PORTION OF THE SURFACE IS COVERED WITH AN ADDITIVE SELECTED FROM THE GROUP CONSISTING OF A SULFITE, A HYDROXYLAMINE OR A BENZOIC OR SULFONIC ACID COMPOUND | KONICA CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5552851-A | Automatic processing machine for silver halide photographic light-sensitive materials | KONICA CORPORATION (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0678781-A1 | Solid processing agent for silver halide photographic light-sensitive materials | KONICA CORPORATION (JP) | 1995-10-25 | — | — | EP | disclosed |
| US-5400105-A | Automatic processing machine for silver halide photographic light-sensitive materials | KONICA CORPORATION (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0595312-A1 | Automatic processing machine for silver halide photographic light-sensitive materials | KONICA CORPORATION (JP) | 1994-05-04 | — | — | EP | disclosed |