Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8062422 | 0.85 | SMN1; SMN2 (0.72) | SMN1; SMN2NPC1RAB9ALMNABCAT2 | |
| SCHEMBL5704283 | 0.85 | SMN1; SMN2 (0.72) | SMN1; SMN2NPC1RAB9ALMNABCAT2 | |
| SCHEMBL10441979 | 0.85 | SMN1; SMN2 (0.72) | SMN1; SMN2NPC1RAB9ALMNABCAT2 | |
| SCHEMBL350453 | 0.83 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9ALMNABCAT2 | |
| SCHEMBL7739354 | 0.83 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9ALMNABCAT2 | |
| SCHEMBL1624911 | 0.83 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9ALMNABCAT2 | |
| SCHEMBL12546804 | 0.83 | MTNR1A (0.51) | SMN1; SMN2NPC1RAB9ALMNABCAT2 | |
| SCHEMBL28335620 | 0.82 | NPC1 (0.56) | SMN1; SMN2NPC1RAB9ALMNATAAR1 | |
| SCHEMBL885090 | 0.81 | BCAT2 (0.68) | SMN1; SMN2NPC1RAB9ALMNABCAT2 | |
| SCHEMBL50338 | 0.81 | BCAT2 (0.68) | SMN1; SMN2NPC1RAB9ALMNABCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844992-B1 | PROCESS FOR PRODUCING BETA-AMINO-ALPHA-HYDROXYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF | DEGUSSA (DE) | 2000-05-24 | — | — | EP | disclosed |
| US-5932758-A | Process for the production β-amino-α-hydroxycarboxylic acids and derivatives thereof | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1999-08-03 | — | — | US | disclosed |
| EP-0844992-A1 | PROCESS FOR PRODUCING $g(b)-AMINO-$g(a)-HYDROXYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF | Degussa Aktiengesellschaft (DE) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997002236-A1 | PROCESS FOR PRODUCING β-AMINO-α-HYDROXYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1997-01-23 | — | — | WO | disclosed |