Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.60 |
| ▸ | THRA | P10827 | 8/20 | 0.60 |
| ▸ | PPARG | P37231 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | TTR | P02766 | 2/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | RXRA | P19793 | 2/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047743 | 1.00 | THRB (0.60) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL17612145 | 0.90 | THRB (0.61) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL8731461 | 0.88 | THRB (0.51) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL12844205 | 0.87 | THRB (0.67) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL468892 | 0.86 | THRB (0.69) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL28626300 | 0.86 | THRB (0.65) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL468893 | 0.86 | THRB (0.69) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL11190023 | 0.85 | THRB (0.64) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL11190025 | 0.85 | THRB (0.64) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL13949745 | 0.85 | THRB (0.64) | THRBTHRAPPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303284-B2 | Immunological method for the determination of free haptenic substances | BRAHMS DIAGNOSTICA GMBH (DE) | 2000-05-03 | — | — | EP | disclosed |
| US-5336621-A | Divalent hapten derivatives | HOECHST CELANESE CORPORATION (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0183901-B1 | BIFUNCTIONAL HAPTENS, METHOD FOR THEIR PRODUCTION AND THEIR USE | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-07-08 | — | — | EP | disclosed |
| US-H1018-H | Immunological method for the determination of free substances having hapten properties | HENNING BERLIN GMBH CHEMIE- UND PHARMAWERK (DE) | 1992-01-07 | — | — | US | disclosed |
| EP-0303284-A1 | Immunological method for the determination of free haptenic substances | B.R.A.H.M.S Diagnostica GmbH (DE) | 1989-02-15 | — | — | EP | disclosed |
| US-4760142-A | Divalent hapten derivatives | HOECHST CELANESE CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |
| EP-0078477-B1 | FENCLOFENAC AS TBP BLOCKING AGENT IN IODOTHYRONINE IMMUNOASSAYS | MILES LABORATORIES, INC. (US) | 1986-09-10 | — | — | EP | disclosed |
| EP-0183901-A2 | Bifunctional haptens, method for their production and their use | BEHRINGWERKE Aktiengesellschaft (DE) | 1986-06-11 | — | — | EP | disclosed |
| US-4468469-A | Substituted phenylacetic acids and salts as TBP blocking agents in iodothyronine immunoassays | MILES LABORATORIES, INC. (US) | 1984-08-28 | — | — | US | disclosed |
| EP-0078477-A2 | Fenclofenac as TBP blocking agent in iodothyronine immunoassays | MILES LABORATORIES, INC. (US) | 1983-05-11 | — | — | EP | disclosed |
| US-4332784-A | SELENIUM USED IN THYROID RADIOIMMUNOASSAY | THE RADIOCHEMICAL CENTRE LIMITED (GB) | 1982-06-01 | — | — | US | disclosed |
| US-4331808-A | Chemiluminescent naphthalene-1,2-dicarboxylic acid hydrazide-labeled haptens | MILES LABORATORIES, INC. (US) | 1982-05-25 | — | — | US | disclosed |
| US-4311853-A | Selenium derivatives of thyroxine and tri-iodothyronine | THE RADIOCHEMICAL CENTRE LIMITED (GB) | 1982-01-19 | — | — | US | disclosed |
| US-4297273-A | MEDICAL DIAGNOSIS; IMMUNOASSAY | MILES LABORATORIES, INC. (US) | 1981-10-27 | — | — | US | disclosed |
| US-4261893-A | INTERMEDIATES IN SYNTHESIS OF CHEMILUMINESCENT-LABELED CONJUGATES USED IN IMMUNOASSAYS | MILES LABORATORIES, INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4238395-A | INTERMEDIATE OF CHEMILUMINESCENT NAPHTHALENE-1,2-DICARBOXYLIC ACID HYDRAZIDE-LABELED CONJUGATES | MILES LABORATORIES, INC. (US) | 1980-12-09 | — | — | US | disclosed |
| US-4226993-A | INTERMEDIATES FOR CHEMILUMINESCENT LABELED CONJUGATES | MILES LABORATORIES, INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4226992-A | INTERMEDIATES FOR CHEMILUMINESCENT LABELED CONJUGATES | MILES LABORATORIES, INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4225485-A | Chemiluminescent naphthalene-1,2-dicarboxylic acid hydrazide-labeled polypeptides and proteins | MILES LABORATORIES, INC. (US) | 1980-09-30 | — | — | US | disclosed |
| US-4212805-A | INTERMEDIATES OF PHTHALHYDRAZIDE-LABELED CONJUGATES | MILES LABORATORIES, INC. (US) | 1980-07-15 | — | — | US | disclosed |