Diphenylacetic Acid

Diphenylacetic Acid

SCHEMBL8047758

CCOc1ccc(C(O)O)cc1.O=C(O)C(c1ccccc1)c1ccccc1.O=C(O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.51

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.51
AKR1C3 P42330 1/20 0.48
AKR1C2 P52895 1/20 0.48
KMT2A Q03164 5/20 0.47
MEN1 O00255 3/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
GAA P10253 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
LTA4H P09960 1/20 0.46
FFAR1 O14842 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 3/20 0.44
LMNA P02545 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CSNK1D P48730 1/20 0.44
NPC1 O15118 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylacetic Acid SCHEMBL8037692 0.83 ACP3 (0.54) CNR2KMT2ACYP3A4GAAL3MBTL1
SCHEMBL13558759 0.82 NQO1 (0.64) CNR2AKR1C3AKR1C2KMT2AMEN1
SCHEMBL1412642 0.80 L3MBTL1 (0.62) CNR2KMT2AMEN1CYP1A2CYP3A4
Diphenylacetic Acid SCHEMBL8941679 0.80 MAPT (0.53) KMT2AMEN1CYP3A4GAACYP2C9
Diphenylacetic Acid SCHEMBL8047740 0.80 LMNA (0.56) KMT2AMEN1CYP2D6L3MBTL1LMNA
SCHEMBL8047756 0.79 KMT2A (0.53) CNR2AKR1C3AKR1C2KMT2AMEN1
SCHEMBL2846564 0.79 HDAC4 (0.64) CNR2KMT2AMEN1CYP1A2CYP3A4
SCHEMBL11603275 0.79 MEN1 (0.57) CNR2KMT2AMEN1CYP1A2CYP3A4
SCHEMBL11420513 0.79 LTA4H (0.57) CNR2KMT2AMEN1CYP1A2CYP3A4
SCHEMBL23053351 0.77 AKR1C3 (0.55) CNR2AKR1C3AKR1C2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5648196-A Water-soluble photoinitiators CORNELL RESEARCH FOUNDATION, INC. (US) 1997-07-15 US claimed
US-5532106-A MICROELECTRONICS WITH POLYMERS, PHOTOACTIVE AGENTS AND DISSOLUTION INHIBITORS CORNELL RESEARCH FOUNDATION, INC. (US) 1996-07-02 US claimed
US-6013413-A Alicyclic nortricyclene polymers and co-polymers CORNELL RESEARCH FOUNDATION, INC. (US) 2000-01-11 US disclosed
US-5648196-A Water-soluble photoinitiators CORNELL RESEARCH FOUNDATION, INC. (US) 1997-07-15 US disclosed
US-5585223-A RADIATION ACTIVATION; HEATING; ETCHING CORNELL RESEARCH FOUNDATION, INC. (US) 1996-12-17 US disclosed
US-5532106-A MICROELECTRONICS WITH POLYMERS, PHOTOACTIVE AGENTS AND DISSOLUTION INHIBITORS CORNELL RESEARCH FOUNDATION, INC. (US) 1996-07-02 US disclosed