SCHEMBL8048320

SCHEMBL8048320

C=CNC(=Cc1ccccc1)S(=O)(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
TSHR P16473 3/20 0.36
AKR1C3 P42330 2/20 0.36
TRPM8 Q7Z2W7 1/20 0.36
AKR1C1 Q04828 1/20 0.35
MCL1 Q07820 1/20 0.35
RECQL P46063 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA7 P43166 1/20 0.35
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6756769 0.78 TGM2 (0.43) ALDH1A1AKR1C3AKR1C1MCL1RECQL
SCHEMBL7784353 0.78 HPGD (0.43) ALDH1A1LMNAPOLBMAPTHPGD
SCHEMBL8722671 0.76 MAPT (0.50) ALDH1A1TSHRAKR1C1CA1CA2
SCHEMBL1244502 0.72 TSHR (0.39) ALDH1A1TSHRAKR1C3AKR1C1FBP1
SCHEMBL9234915 0.71 MCL1 (0.44) ALDH1A1TSHRAKR1C3AKR1C1MCL1
SCHEMBL2543854 0.70 TSHR (0.45) ALDH1A1TSHRAKR1C3AKR1C1FBP1
SCHEMBL8913897 0.70 TSHR (0.45) ALDH1A1TSHRAKR1C3AKR1C1HTT
Sulfuric Acid SCHEMBL28965109 0.69 TSHR (0.43) ALDH1A1TSHRAKR1C3AKR1C1FBP1
Styrene SCHEMBL1672302 0.69 ALDH1A1 (0.64) ALDH1A1TSHRMCL1RECQLCA1
Ammonia Solution, Strong SCHEMBL18492497 0.69 TSHR (0.43) ALDH1A1TSHRAKR1C3AKR1C1FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6086764-A Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use CROSSWINDS, INC. (US) 2000-07-11 US claimed
EP-0884096-A1 Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use Crosswinds, Inc. (US) 1998-12-16 EP claimed
US-6086764-A Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use CROSSWINDS, INC. (US) 2000-07-11 US disclosed