Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 4/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043658 | 0.72 | — | — | |
| SCHEMBL8044837 | 0.70 | — | — | |
| SCHEMBL8044636 | 0.70 | — | — | |
| SCHEMBL8047472 | 0.67 | RAB9A (0.49) | — | |
| SCHEMBL8046649 | 0.64 | — | — | |
| SCHEMBL8044098 | 0.59 | POLB (0.35) | — | |
| SCHEMBL4877279 | 0.55 | ALDH1A1 (0.38) | — | |
| SCHEMBL8043101 | 0.54 | — | — | |
| SCHEMBL7819034 | 0.52 | KDM4E (0.38) | — | |
| SCHEMBL8044128 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |