Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048177 | 0.78 | RAB9A (0.37) | CASP3MAPTNPC1RAB9A | |
| SCHEMBL8032801 | 0.78 | CYP2A6 (0.42) | MAPT | |
| SCHEMBL770898 | 0.70 | POLB (0.44) | POLBCASP3MAPTRXFP1NPC1 | |
| SCHEMBL7818670 | 0.65 | KDM4E (0.41) | POLBCASP3MAPTNPC1RAB9A | |
| SCHEMBL519565 | 0.63 | MAPK1 (0.44) | POLBCASP3MAPTRXFP1 | |
| SCHEMBL8043658 | 0.60 | — | — | |
| SCHEMBL2195598 | 0.60 | POLB (0.38) | POLBCASP3MAPTRXFP1NPC1 | |
| SCHEMBL16593598 | 0.60 | POLB (0.38) | POLBCASP3MAPTRXFP1NPC1 | |
| SCHEMBL7388070 | 0.60 | PTGS2 (0.46) | POLBCASP3MAPTRXFP1NPC1 | |
| SCHEMBL15424781 | 0.60 | PDPK1 (0.47) | POLBCASP3MAPTRXFP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |