Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 5/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7114230 | 0.79 | FBP1 (0.70) | FBP1PDK1ALDH1A1TSHRNOS1 | |
| SCHEMBL8043078 | 0.78 | FBP1 (0.47) | FBP1PDK1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL8044127 | 0.74 | FBP1 (0.42) | FBP1PDK1HTR7 | |
| SCHEMBL8048705 | 0.74 | FBP1 (0.46) | FBP1PDK1ALDH1A1TSHRICAM1 | |
| SCHEMBL8047678 | 0.74 | FBP1 (0.42) | FBP1PDK1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8046775 | 0.74 | FBP1 (0.42) | FBP1PDK1ALDH1A1TSHRMAPK1 | |
| SCHEMBL8044770 | 0.74 | FBP1 (0.43) | FBP1PDK1ALDH1A1HTR7 | |
| SCHEMBL9100372 | 0.73 | FBP1 (0.45) | FBP1PDK1ALDH1A1TSHRNOS1 | |
| SCHEMBL8033947 | 0.72 | F2 (0.45) | FBP1PDK1ALDH1A1TSHRMAPK1 | |
| SCHEMBL8031756 | 0.71 | FBP1 (0.44) | FBP1PDK1MAPK8MAPK9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |