Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 6/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.39 |
| ▸ | RELA | Q04206 | 6/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 12/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048594 | 0.70 | NFKB1 (0.72) | NFKB1NFKB2RELA | |
| SCHEMBL10740193 | 0.69 | NFKB1 (0.41) | NFKB1NFKB2RELALTB4RLTB4R2 | |
| SCHEMBL7207989 | 0.69 | NFKB1 (0.41) | NFKB1NFKB2RELALTB4RLTB4R2 | |
| SCHEMBL4202427 | 0.68 | LTB4R (0.41) | NFKB1NFKB2RELALTB4RLTB4R2 | |
| SCHEMBL14457146 | 0.67 | LTB4R (0.45) | NFKB1NFKB2RELALTB4RLTB4R2 | |
| SCHEMBL23911581 | 0.66 | NFKB1 (0.41) | NFKB1NFKB2RELALTB4RLTB4R2 | |
| SCHEMBL4794533 | 0.66 | NFKB1 (0.41) | NFKB1NFKB2RELALTB4RLTB4R2 | |
| SCHEMBL10511106 | 0.66 | PPARG (0.43) | NFKB1NFKB2RELALTB4RLTB4R2 | |
| SCHEMBL7552940 | 0.66 | LTB4R (0.47) | NFKB1NFKB2RELALTB4RLTB4R2 | |
| SCHEMBL7557806 | 0.66 | LTB4R (0.47) | NFKB1NFKB2RELALTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100268-A | MIGRAINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2000-08-08 | — | — | US | disclosed |
| EP-0714396-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005383-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-02-23 | — | — | WO | disclosed |