Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038626 | 0.74 | GRIN2B (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8053071 | 0.73 | DPP4 (0.51) | KDM1ACTSLCTSBCTSK | |
| SCHEMBL23809773 | 0.69 | CARM1 (0.45) | MAOAMAOBCTSLCTSBCTSS | |
| SCHEMBL1609623 | 0.68 | MAOA (0.58) | MAOAMAOBCTSLCTSBCTSS | |
| SCHEMBL25992610 | 0.68 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CYP2A6HTR2A | |
| SCHEMBL16499615 | 0.68 | MAOA (0.50) | TDP1MAOAMAOBCTSLCTSB | |
| SCHEMBL16499614 | 0.68 | MAOA (0.50) | TDP1MAOAMAOBCTSLCTSB | |
| SCHEMBL16499700 | 0.68 | MAOA (0.50) | TDP1MAOAMAOBCTSLCTSB | |
| SCHEMBL25901694 | 0.68 | TDP1 (0.46) | TDP1MAOAMAOBCTSLCTSB | |
| SCHEMBL25412651 | 0.68 | MAOA (0.40) | MAOAMAOBCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080750-A | FOR PROPHYLAXIS AND TREATMENT OF DISEASES CAUSED BY INFECTION BY ROTAVIRUS | NIPPON SHOJI KAISHA LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0806418-A2 | Novel pyrimidine compound and anti-rotavirus agent | NIPPON SHOJI KAISHA, LIMITED (JP) | 1997-11-12 | — | — | EP | disclosed |