Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609623 | 0.73 | MAOA (0.58) | CARM1PRMT6MAOAMAOBCTSL | |
| SCHEMBL20005916 | 0.73 | MAOA (0.40) | MAOAMAOBCTSLCTSBCTSS | |
| SCHEMBL25412651 | 0.73 | MAOA (0.40) | MAOAMAOBCTSLCTSBCTSS | |
| SCHEMBL11959525 | 0.71 | GRIN2B (0.44) | MAOAMAOBCTSLCTSBCTSS | |
| SCHEMBL10071184 | 0.70 | CARM1 (0.65) | CARM1PRMT6MAOAMAOBCTSL | |
| SCHEMBL705394 | 0.70 | CTSS (0.56) | MAOAMAOBCTSSCTSKSLC18A2 | |
| SCHEMBL7756938 | 0.70 | OPRM1 (0.58) | MAOAMAOBCTSSCTSKSLC18A2 | |
| SCHEMBL19188155 | 0.69 | MAOA (0.50) | CARM1PRMT6MAOAMAOBCTSL | |
| Benzenethiol SCHEMBL4798128 | 0.69 | MAOA (0.50) | CARM1PRMT6MAOAMAOBCTSL | |
| SCHEMBL10091167 | 0.69 | ACHE (0.53) | CARM1PRMT6MAOAMAOBSLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615534-B1 | FUSED PENTACYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SRL (BE) | 2021-09-15 | — | — | EP | disclosed |