Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.54 |
| ▸ | MMP9 | P14780 | 11/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 9/20 | 0.54 |
| ▸ | MMP1 | P03956 | 8/20 | 0.46 |
| ▸ | ADAM33 | Q9BZ11 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MMP15 | P51511 | 1/20 | 0.40 |
| ▸ | MMP16 | P51512 | 1/20 | 0.40 |
| ▸ | SDCBP | O00560 | 1/20 | 0.39 |
| ▸ | SDC2 | P34741 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627441 | 0.86 | MMP2 (0.75) | MMP2MMP9ADAM17MMP1ADAM33 | |
| SCHEMBL6626012 | 0.74 | ADAM17 (0.62) | MMP2MMP9ADAM17MMP1ADAM33 | |
| SCHEMBL6628657 | 0.73 | MMP2 (0.78) | MMP2MMP9ADAM17MMP1ADAM33 | |
| SCHEMBL6628166 | 0.71 | MMP2 (0.74) | MMP2MMP9ADAM17MMP1ADAM33 | |
| SCHEMBL6628455 | 0.71 | MMP9 (1.00) | MMP2MMP9ADAM17MMP1ADAM33 | |
| SCHEMBL6628135 | 0.69 | MMP2 (0.70) | MMP2MMP9ADAM17MMP1ADAM33 | |
| SCHEMBL6627939 | 0.69 | MMP9 (0.80) | MMP2MMP9ADAM17MMP1ADAM33 | |
| SCHEMBL6626999 | 0.69 | MMP2 (0.84) | MMP2MMP9ADAM17MMP1ADAM33 | |
| SCHEMBL6627183 | 0.68 | ADAM17 (0.52) | MMP2MMP9ADAM17MMP1ADAM33 | |
| SCHEMBL6628080 | 0.67 | ADAM17 (0.74) | MMP2MMP9ADAM17MMP1ADAM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057336-A | ANTIINFLAMMATORY AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-02 | — | — | US | disclosed |