SCHEMBL8049768

SCHEMBL8049768

c1ccc(-c2ccc(-c3ccccc3)c(-c3ccccc3)[o+]2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.36
ALOX5 P09917 1/20 0.35
ALDH1A1 P00352 5/20 0.35
HSD17B10 Q99714 2/20 0.34
CYP2A6 P11509 2/20 0.34
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP2B6 P20813 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
PTGS2 P35354 2/20 0.32
AURKA O14965 1/20 0.32
CDK1 P06493 1/20 0.32
LYN P07948 1/20 0.32
PIM1 P11309 1/20 0.32
FGFR1 P11362 1/20 0.32
PRKACA P17612 1/20 0.32
RPS6KB1 P23443 1/20 0.32
CDK2 P24941 1/20 0.32
MARK3 P27448 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perchlorate SCHEMBL11552227 0.71 ALDH1A1 (0.38) BACE1ALDH1A1HSD17B10CYP2A6HPGD
SCHEMBL11878001 0.71 BACE1 (0.45) BACE1ALOX5ALDH1A1HSD17B10HPGD
SCHEMBL29968344 0.71 SQOR (0.39) BACE1ALOX5ALDH1A1HSD17B10CYP2A6
SCHEMBL11856656 0.69 ALDH1A1 (0.47) BACE1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL7579939 0.68 BACE1 (0.41) BACE1ALOX5ALDH1A1HSD17B10CYP2A6
SCHEMBL5671404 0.65 ALDH1A1 (0.41) BACE1ALDH1A1HSD17B10CYP2A6HPGD
SCHEMBL29672996 0.65 ALDH1A1 (0.41) BACE1ALDH1A1HSD17B10CYP2A6HPGD
Perchlorate SCHEMBL7161260 0.64 RAB9A (0.47) BACE1ALDH1A1MAPK1
SCHEMBL29728323 0.63 ALDH1A1 (0.53) BACE1ALOX5ALDH1A1HSD17B10CYP2A6
SCHEMBL3415539 0.63 ALDH1A1 (0.53) BACE1ALOX5ALDH1A1HSD17B10CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6011180-A Acid-stable borates for photopolymerization CIBA SPECIALTY CHEMICALS CORPORATION 2000-01-04 US disclosed